Rosen Center Pilot Grant Awards

Rosen Bioengineering Center Pilot Research Grants provide up to $80,000 to support collaborative early-stage projects that require sharing of ideas, people and resources between labs. The goal of the program is to help teams develop strong preliminary data that will enhance their competitiveness for large, collaborative awards from external agencies like NIH, NSF, DoD and others.

The teams involved in this program have generated published manuscripts (with others in prep or submitted), given numerous conference presentations, submitted multiple proposals for external funding, and received follow-on awards from Federal agencies.


    Title: A smart microcapsule for continuous gut metabolic monitoring

    Awardees: Wei Gao and Azita Emami

    Title: Acoustic metamaterials for non-invasive neural imaging

    Awardees: Chiara Daraio and Mikhail Shapiro

    Title: Advanced sample preparation for cryo-electron microscopy with single-molecule control

    Awardees: Rebecca Voorhees and Michael Roukes

    Title: Cell type specific in situ brain engineering by in vivo gene editing

    Awardees: Yuki Oka and Matt Thomson

    Title: Engineering population regulation of the gut microbiome to regulate inflammation in mouse models

    Awardees: Sarkis Mazmanian and Richard Murray

    Title: Bacterial argonaute proteins as novel tools for genome engineering

    Awardees: Alexei Aravin and Stephen Mayo


    Title: Proving the possibility of multiplexed single-cell RNA sequencing of bacteria

    Awardees: Rustem Ismagilov and Matt Thomson

    Title: Selective killing of latently-infected CD4+ T-cells by conditionally replicating viruses that detect HIV transcripts

    Awardees: Pamela Bjorkman and Niles Pierce

    Title: Genetically encoded magnetoreceptors for noninvasive control of cellular function

    Awardees: Mikhail Shapiro, Markus Meister and Carlos Lois


    Title: Engineered viruses for large-scale targeted genetic manipulation in mice

    Awardees: Carlos Lois and Viviana Gradinaru

    Title: Constraining the mechanisms of extracellular electron transfer (EET) in Pseudomonas aeruginosa biofilms by studying the effects of eDNA-binding on phenazine reactivity

    Awardees: Dianne Newman and Jacqueline Barton

    Title: A Miniature, wireless and implantable intraocular pressure sensor

    Awardees: Yu-Chong Tai and Azita Emami

    Title: 3-Dimensional Nano-Architectures for In-Vivo Biomedical Measurements

    Awardees: Julia Greer and Joel Burdick

    Title: Visualizing nicotine entry into midbrain dopaminergic neurons

    Awardees: Henry Lester and Changhuei Yang


    Title: Dynamic single-cell imaging of long-range physical interactions among regulatory DNA elements and target genes

    Awardees: Ellen Rothenberg and Barbara Wold

Past Rosen Research Project Awards

    Frances Arnold and Richard Murray “Systems Engineering of Microbial Stress Response”

    John O. Dabiri for graphic design services to develop visual elements for an advanced biomechanics textbook

    Chin Lin Guo “Engineering Self-assembled Tubular Systems”

    Richard Murray “Forced Response Analysis of Biomolecular Circuits”

    Richard Murray, iGEM Team funding to allow a group of Caltech undergraduate students to compete in the International Genetically Engineered Machine competition

    Rob Phiillips “Teaching at the Interface: A Vision for Quantitative Biology”

    Erik Winfree hosted the 17th International Conference on DNA Computing and Molecular Programming (DNA17) at Caltech